靠右心室起搏的婴儿产生了双心室起搏由此导致了心力衰竭病例英文.ppt

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1、TC YungPaediatric Cardiology UnitGrantham HospitalHong Kong,Biventricular pacing in a baby with RV pacing induced heart failure,The 10th South China International Congress of Cardiology,Guangzhou,2008,Male babyAntenatalat 21 week of gestation noted have bradycardia and AV blockmother anti Ro,RF+ve L

2、SCS at 35 weeks for progressive fetal heart failure,birth weight 2.36 kgPost-natal Respiratory distressCXR:cardiomegaly,CT ratio 67%Put on nasal CPAP+Isoprenaline infusion,CT ratio 67%,Transfer to TGH on the day of birthEcho showed normal heart structure,LVSF 38.9%,LVEDD 2.78cm LVEF 77.2%HR 50-60/mi

3、n,systolic BP 55mmHg while on isoprenaline infusion,Epicardial pacemaker insertion the second day after admissionRA RV(inferior wall)pacing DDD(90-180/min),Post epicardial DDD pacing:CT ratio 67.9%,Measurement at Operation Leads 4965 steroid-eluted leads for both RA and RV Generator-Sensia SE DR 01

4、DDDRImpedance-V lead 589-A lead 343 A pacing threshold-1.8V 0.5msV pacing threshold-1.6V 0.5ms R wave8.8mvP wave3.4mv,Paradoxical septal motion,LVEDD 2.1cm,FS 25.3%,LVEF 58%,3 days after RV pacing,ECHO post DDD pacing:,ECHO before DDD pacing:,Pericardial effusion,Short axis view,Long axis view,Day 1

5、2 post pacing,Surgical drainage of pericardial fluid(30cc),LVEDD 2.76cm,FS 14.6%,EF 37.8%Dilated LV cavity,3 weeks post pacingDischarge from hospital with diuretics Pacing rate 70-180/min,3.5 months post RV pacingSignificant heart failure symptom:tachypnea and fluid retentionEcho-dilated LV,LVEDD 3.

6、3 cm-Moderate tricuspid and mitral incompetence Poor LV contraction,LVFS 5%LVEF 14.3%ECG showed irregular rhythm,Wenckebach phenomenon due to rapid atrial rate while on DDD pacingPace mode changed to VVI 130/minHospitalized for dobutamine infusion,ECHO progressive LV dilatation,Severe LV dysynchrony

7、,LVPW Septal delay 255ms,3 days after admissionWhen VVI turned off intrinsic escape rhythm,synchronized LV contraction pacing rate to 55/min and started isoprenaline to promote synchronized contraction,But heart failure continued to deteriorateThe baby was intubated for 5 daysRV pacing rate was incr

8、eased to 120/minPlan Biventricular epicardial pacing,LV epicardial pacing LV lead threshold=1.0 v,0.4msRV/LV delay=4ms(LV first),1 day after biventricular pacing,Post bivent pacingLVPW Septal delay 65ms,DDD RV pacing LVPW Septal delay 255ms,Second day post biventricular pacingLVEDD 3.24cm,LVSF 20.6%

9、,mild mitral incompetence,Second day post biventricular pacing Sense AV intervals VTI of LVOT50ms8.380ms9.1100ms9.1120ms8.5140ms5.8 V-V delay LV first VTI of LVOT(sense AV 100ms)4 ms7.812ms7.520ms6.8 40ms7.5,Biventricular pacing QRD duration:100 ms,Post epicardial DDD(RA RV)pacing 90-180 ppm QRS dur

10、ation 120 ms,DDD RV pacing QRS duration:120 ms,Biventricular pacing QRD duration:100 ms,1 week after Bivent pacing Home with diuretics and ACEILVEDD 3.19cm,LVSF 20.2%LVEF 49.3%Septal-LVPW delay 65ms10 days after Bivent pacing LVEDD 3.02cm,LVSF 26.7%,LVEF 60.0%17 days after Bivent pacing LVEDD 2.51cm

11、,LVSF 27.8%,LVEF 62.5%4 weeks post Bivent pacingLVEDD 2.4cm,LVSF 33%LVEF 69.9%,3 weeks after Bivent pacing,5 months post Bivent pacingLVEDD 2.5cm,LVSF 44%,LVEF 82%no mitral incompetenceOff medication,9 months post biventrcular pacing LVEDD 2.32cm,FS 32.5%LVEF 67.2%,LV size and LV ejection fraction,c

12、m,Bivent pacing,Admission for heart failure,Summary:RV pacing may occasionally induced severe LV dysfunction secondary to LV dysynchronyLV dysfunction may be evident within 2 weeks after RV pacing and progress to dilated cardiomyopathyBiventricular pacing(CRT)can correct the LV dysynchrony and the dilated cardiomyopathy,Post epicardial DDD(RA RV)pacing 90-180 ppm QRS duration 120 ms,5 months post Bivent pacingLVEDD 2.5cm,LVSF 44%,LVEF 82%no mitral incompetenceOff medication,