《呕血与便血》PPT课件.ppt

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1、呕血与便血Hematemesis and Hematochezia,Definition,Hematemesis:Bloody vomitus from the upper gastro-intestinal(GI)tract（before the ligament of Treitz)Hematochezia:bright red,maroon or black blood from the rectum,Treitz:The ligament of Treitz is an anatomic landmark for the duodenal-jejunal junction,Clinic

2、al Manifestation,1 Manner of bleeding presentation2 Hypovolemia(低血容量)or shock3 Anemia(贫血),Patients manifest blood loss,(A)Hematemesis 呕 血 Character Bloody vomitus,either fresh and bright red or older and“coffee-ground”(hematin 酸化正铁血红素),Manner of bleeding presentation,from the GI tract in five ways:,

3、cause of disease,90%upper GI bleeding is due to four lesions:1)peptic ulcer(消化性溃疡)2)esophageal or gastric varices(食管胃底静脉曲张破裂)3)hemorrhagic gastritis(急性糜烂性出血性胃炎)4)gastric cancer,peptic ulcer,hemorrhagic gastritis,esophageal varices,gastric cancer,Other causes of upper GI bleeding,Mallory-Weiss tear食道

4、-贲门撕裂伤 Foreign body in esophagus 食管异物 Ancylostomiasis 钩虫病 Post-sphincterotomy 括约肌切开术后,Differentiation Nosebleeding?Hemoptysis?,Differntiating hemoptysis and hematemesis,Manner of bleeding presentation,(B)Hematochezia 便 血 Character bright red or maroon blood from the rectum pure blood blood intermixe

5、d with formed stool bloody diarrhea,(C)Melena 黑 便 Character Shiny,black,sticky,foul-smelling stool Tarry stool(柏油样便)(degradation of blood)Differentiation exogenous stool darkeners:animal blood,iron,bismuth(铋剂),Manner of bleeding presentation,Manner of bleeding presentation,(D)Stool with occult blood

6、 隐血便 Detected only by testing the stool with a monoclonal antibody for human hemoglobin,Estimate amount of bleeding from upper GI tract,510 ml/d OB+5070 ml/d Melena 250300 ml in short time Hematemesis,Causes of bleeding,Colorectal cancer Colitis Large hemorrhoid 大痔 Rectum tear 肛裂 Vascular anomalies

7、Hematologic diseases,Manner of bleeding presentation,(E)without any objective sign of bleeding,with symptoms of blood loss,1.Hypovolemia or shock,Depending on speed and volume of blood loss1000mL:Weakness,giddiness(眩晕),tachycardia(心动过速),cold extremity,sweatingShock:hypotention(低血压),oliguria,(少尿),2.A

8、nemia and hemogram changing If blood loss is acute,the hematocrit(红细胞比容)dose not change during the first few hours after hemorrhage About 24 to 72 hours later,plasma volume is larger than normal and the hematocrit is at its lowest point,bleeding slowly hypochromic(血红蛋白过少)microcytic(小细胞)red blood cel

9、ls mean corpuscular volume(MCV，平均血球压积)of the cells may be low,Hematocrit changesA Before bleedingB Immediately after bleedingC 2472 hours after bleeding,3.Fever,low grade fever in 24 hours after bleeding,4.Azotemia(氮质血症),Degradation of protein in intestinal tract BUN in several hours after bleeding

10、up to the peak in about 24-48 hours normal after 3-4days,5.Bowel sound Active bowel sound usually be presented in acute bleeding from GI tract,Where is the source of bleeding?Localization,Upper GI bleeding:bleeding from a source proximal to the ligament of TreitzLower GI bleeding:bleeding from a sit

11、e distal to the ligament of Treitz,Localization,Differentiating features of upper GI and lower GI bleedingUpper GILower GIManifestationHematemesisHematocheziamelenaNasogastric aspirateBloodyClearBUNElevatedNormalBowel soundHyperactiveNormal,Upper GI tract bleeding?,Clinical manifestation(hematemesis

12、melena)Bowel soundNasogastric tube,Hematemesis,Melena,Hematochezia,More proximal lesions produce hematemesis or melena,whereas more distal lesions are more likely to produce hematochezia,Diagnostic approach,1.History and physical examination2.Laboratory examination3.Auxiliary examination,History and

13、 physical examination,A history of previously documented GI tract disease determined by radiography,endoscopy,or surgical procedures is very useful,Diagnostic approach to GI bleeding,Diagnostic approach to GI bleeding,A history of epigastric(上腹部)burning pain promptly relieved by food or antacids(抗酸剂

14、)or nocturnal(夜间)pain suggests peptic ulcer disease,particularly duodenal(十二指肠)ulcer,Diagnostic approach to GI bleeding,Patients with stigmata(特征)of hepatitis B or other chronic active liver disease e.g spider angioma(蜘蛛痣),ascites(腹水),gynecomastia(男性乳房发育)may present with painless hematemesis from es

15、ophageal varices,Diagnostic approach to GI bleeding,Patients with forceful,retching(干呕)or multiple episodes of vomiting of food prior to the onset of hematemesis may be bleeding from MalloryWeisstears of the gastro-esophageal junction,Diagnostic approach to GI bleeding,A history of gradual weight lo

16、ss intermittent blood in the stools altered bowel habitsoften suggests colorectal malignancy,Diagnostic approach to GI bleeding,Hemorrhoidal bleeding is often suggested by the presence of bright red blood surrounding well-formed,normal-appearing stools,Diagnostic approach to GI bleeding,A rectal exa

17、mination is essential to document stool color as well as to palpate for gross anorectal(肛直肠)mass lesions such as polyps(息肉),cancers,or large hemorrhoids.,Diagnostic approach to GI bleeding,Auxiliary examinationEndoscopy(内镜)Endoscopy is the diagnostic procedure of choice because of its high accuracy

18、and immediate therapeutic potential.Endoscopy,however,must be performed only following adequate resuscitation(复苏),Diagnostic approach to GI bleeding,Barium radiography(钡餐)Barium radiography is noninvasivebut has significant disadvantages,particularly in patients who are bleeding actively,Diagnostic

19、approach to GI bleeding,Angiography(血管造影)Angiography may localize the site of bleeding Bleeding must be active because angiography detects only extravasation(外渗)of contrast(造影剂)into the GI tract,Is bleeding acute or chronic?,Intensive care,Where is the source of bleeding?,Empiric therapy,Diagnosis,Treatment,(经验治疗),What is the causes of bleeding?,Recognition of hemorrhage,Diagnostic approach,Questions,1.名词解释:呕血 便血 隐血便2.呕血最常见原因有哪些?(至少4种),