scifinder使用教程.ppt
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1、SciFinder Scholar,CAS中国代表处温超W,打开世界科技文献宝库的钥匙,2023/7/8,2,Remember the BIG books?,Chemical Abstracts,the standard reference for chemistry and related sciences,2023/7/8,3,CAS Response to Changing Market Conditions,2023/7/8,4,The entire BIG book is now available through SciFinder and SciFinder Scholar,美国
2、化学文摘社为了适应市场的变化,2023/7/8,5,SciFinder Scholar是“CA网络版”Yes.They are all supplied by CAS-a division of ACS.But NoHave broaden contentMore effective exploration toolsPowerful post-processing,2023/7/8,6,SciFinder Scholar数据库与CACD/Print区别,2023/7/8,7,SciFinder Scholar出品者美国化学文摘社CAS,是美国化学学会ACS的分支机构全球最大的学协会组织一百年
3、的历史以“促进化学知识的增长和传播”为使命,造福于工业和教育事业,2023/7/8,8,ACS出版部门,一直致力于为全球化学研究机构、企业、个人提供高品质的文献资讯及服务,已成为享誉全球的科技出版机构。,High Quality High Impact,2023/7/8,9,ACS重点期刊ACS的出版物内容涵盖了24个主要的领域(共37本刊),2023/7/8,10,Scifinder 介绍 两个主要数据库,-3100多万物质和5800万序列 通过名称、分子式、结构式检索物质或者用 BLAST检索序列 通过实验或者计算得到的物质性质数据 CAS RN每日新增4000多个物质或序列,-摘自950
4、0多种期刊、50多个专利组织以及其他学术题录信息(2640万条信息)通过作者/公司/全文/期刊/专利号/文件类型和出版年检索 CAS RN每日新增3000篇期刊和专利2天内收录7大专利局公开的专利,CAS Registry,CAplus,最全的物质数据库,时效性最高文摘数据库,2023/7/8,11,Scifinder 介绍 四个独特数据库,世界750家厂商850类800多万种化学品商业来源物质CAS RN,1250万条单步或多步反应(尤其专利中的反应)结构和亚结构检索CAS RN每日新增6001300新反应,23万多备案或管控物质 CAS RN每周新增约50种物质,70多个国家4780多种医
5、学类期刊130万条文摘记录美国国立医学图书馆出品每周更新4次,Chemlist,CASReact,Medline,ChemCats,时效性高实用性强,2023/7/8,12,原始出版物,CAS科学家,可检索条目,信息检索者或用户,Scifinder Scholar科学索引过程,2023/7/8,13,2023/7/8,14,SciFinder中的题目Method for preparing reduced glutathione freeze-dried powder for injection.,专利原文的题目Lyophilized powder injection of glutathio
6、ne and preparation process thereof,2023/7/8,15,原文的摘要 SciFinder的摘要,The invention discloses a reduced-type glutathione freeze dried injection and making technique,which is characterized by the following:loading 95.0%-105.0%reduced-type glutathione(C10H17N3O6S)to display white block and powder;testing
7、nitrosoferric sodium cyanide to display red;keeping the consistent reserving time of main peak of sample solution as comparison sample solution with pH value at 5.0-6.5;making dried weight not over 5.0%and the content of relative material not more than 4%;limiting the content of bacterial endotoxin
8、less than 0.125EU;making other items satisfy the standard.,The title freeze-dried powder for injection contains reduced glutathione,pH regulator,supporter and antioxidant.Reduced glutathione is identified by(1)dissolving the freeze-dried powder in sodium hydroxide soln.,adding sodium nitroprusside,s
9、haking for displaying deep red,standing for displaying yellow,and shaking for displaying red again,and(2)testing the content of reduced glutathione by HPLC at 210 nm on C18 column with mobile phase of phosphate(pH 3.0)-methanol(97:3).The content of reduced glutathione must be 95.0%-105.0%of amt.mark
10、ed.The freeze-dried powder has pH value in soln.of 5.0-6.5,drying wt.loss not more than 5.0%,impurities content not more than 4%,and bacterial endotoxin content less than 0.125 EU.The pH regulator comprises sodium hydroxide,potassium hydroxide,sodium carbonate,potassium carbonate,sodium hydrogen car
11、bonate,sodium phosphate,potassium phosphate,disodium hydrogen phosphate.The supporter comprises mannitol,glucose,sorbitol,sodium chloride,dextran,lactose,hydrolytic gelatin,polyethylene glycol and glycine.The antioxidant comprises sodium hydrogen sulfite,sodium thiosulfate,Me p-hydroxybenzoate,Et p-
12、hydroxybenzoate,Pr p-hydroxybenzoate,sodium pyrosulfite or thiourea.The freeze-dried powder for injection possesses stable controllable quality,and improved drug safety for patients.,2023/7/8,16,2023/7/8,17,1双击 sfs2007.exe 文件,开始安装,然后点击 Setup,多数步骤都默认即可;注意在安装过程中,会弹出一个窗口询问:Do you have a disk labled Cus
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