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1、广东省生物医药产业发展概况(1)广东是全国生物医药产业大省,综合实力居全国前列2000年,全国医药工业完成总产值2332亿元,医药商业销售总额完成1509亿元,实现利税总额270亿元。广东省医药工业总产值、销售额、利税,分别排居全国的第二、第一和第一位(见图一和表一)。(2)形成了门类较齐全的产业结构体系广东医药主要由化学药品(以药物制剂为主)、中成药、医疗器械、生物技术药四大领域构成(图二),均在全国有一定的竞争优势。从整体上看,主要产品及技术属于80年代的占61.8%,属于90年代的占25.3%(图三);获国家优质产品金奖28个、部优质产品奖76个、省优质产品奖398个,优质产品率30%以
2、上,可见技术水平在全国居于领先行列。(2)生物高新技术在医药产业广泛应用如基因操作技术、基因芯片技术、蛋白质技术、生物医学工程技术、生物信息技术、超临界二氧化碳萃取技术、膜分离技术等广泛应用于基因工程药物和现代中药的开发。一大批新药如重组人1b干扰素(深圳科兴生物公司)、重组人干扰素(丽珠集团)、G-CSF(深圳新鹏)、GM-CSF(顺德南方生物制药公司)、重组碱性成纤维细胞生长因子(珠海东大生物公司)、重组乙肝疫苗(深圳康泰生物公司)、抗高血压药卡维地络(第一军医大学)、非甾体抗炎新药尼美舒利(广东省药物研究所)、珍珠贝胶囊(中科院南海所)、精制单味中药浓缩颗粒(广东一方制药厂)等开发成功,
3、还有一批药物已进入中试以上阶段,大大促进了我省医药工业的发展。生物技术药品工业是世界公认的21世纪医药发展的主要方向,也是我国高新技术产业的重点领域。截止至2000年年底,全国已批准上市的基因工程药物15种,广东有8种,约占全国的一半。1b干扰素和乙肝疫苗两个品种的市场占有率均在40以上。生物医学工程产业(医疗器械)是我省医药行业发展最快的产业,每年以20以上的速度递增。形成了以大型精密医疗诊断设备、医用监护仪器、超声诊断仪器、家庭保健工程产品为主导的产品体系。其中核磁共振成像装置、介入疗法导管、遥控后装机、X刀等产品已接近国际同类产品的先进水平;伽玛刀处于国际领先地位。(4)中成药工业是传统
4、优势的产业领域广东在中药研究开发方面,技术力量雄厚,科技资源丰富。最突出的是现代中药研制开发系列规范的实施与关键技术发展及应用在全国先行一步,其中药技术创新链之完整,在全国绝无仅有,中药、的实施在全国最早起步,现代新型提取分离技术、中药活性筛选、指纹图谱质控、转基因中药育种、企业ERP应用等关键技术均居全国先进行列,并建立了一系列国家级的研究基地。因此,广东有条件争取在现代中药产业发展中扮演领头羊角色,这也是粤港生物医药产业合作的首选领域。(5)大型企业集团和产业基地不断发展壮大中成药产业有广州药业股份有限公司、广州白云山企业集团、深圳三九集团;基因工程药物产业有深圳科兴生物制品公司、深圳康泰
5、生物公司;生物医学工程产业有深圳安科公司、广东威达公司,汕头超声公司;海洋药物产业有深圳海王集团等。建立了一批现代化生物医药产业基地。如中山健康产业基地是国家批准的两个健康产业基地之一,深圳科兴生物制品公司是国家批准的16个863产业基地之一,珠海-广州建立了国家中药现代化工程技术研究中心,佛山建立了国家医疗保健器具工程技术研究中心,还有广州国际生物岛等。最近已向科技部正式申报建设国家中药现代化科技产业(广东)基地。(6)创新技术平台的建设使广东生物医药产业融入世界中国加入WTO,将对生物医药产业产生巨大的冲击。医药知识产权的保护越来越严格,仿制的路将越走越窄,创新成为医药产业发展的必由之路。
6、近年来广东加大了创新技术平台的建设,已建成2个国家级新药安全性评价(GLP)重点实验室和2个国家级新药临床评价(GCP)中心,建成了广东省海洋药物重点实验室,最近又组建了广东省新药筛选重点实验室,专门从事中药新药、微生物新药的筛选。广东医药产业已走出了融入世界的第一步。内部资料,请勿外传!9JWKffwvG#tYM*Jg&6a*CZ7H$dq8KqqfHVZFedswSyXTy#&QA9wkxFyeQ!djs#XuyUP2kNXpRWXmA&UE9aQGn8xp$R#͑GxGjqv$UE9wEwZ#QcUE%&qYpEh5pDx2zVkum&gTXRm6X4NGpP$vSTT#&ksv
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