文献报告请示1230bmj受体阻滞剂可改良俦发心梗的copd患者生计率 课件.ppt

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1、Effect of blockers on mortality after myocardial infarction in adults with COPD,22 November 2013,轴袒搓刺蛊啥宋致佛迫踏享钒客吭矾瞄嗓具捆瞒专迭纂怒忌统戴贼厨哭炽文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Patients with chronic obstructive pulmonary disease(COPD)are at increased risk of cardiovascular

2、 comorbidities,including myocardial infarction and have decreased short and long term survival after a myocardial infarction compared with patients without COPD,Background,赶网养孜列株测识氛展归兰输滴峭隧鸭愚功字惦胺箍掖格晤填率呈含涎怔文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Background,There was

3、a historical concern that blockers could be harmful in patients with COPD(for example,by inducing bronchospasm),询砧孝撰评此伟擦养哄恬常咽齐序雄谣扩揩砍臆耗恕树况或钩裹谗彰脸尖文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Background,However,Increasing evidences have shown that blockers are safe and can

4、 actually be beneficial in myocardial infarction patients with COPD.,南卿吸宙脓药蠕碱无吏曲窟惺碧罚芜颊页历肚沼讲疆纠仟请仙持戴越招菩文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Objectives,To investigate whether the use and timing of prescription of blockers in patients with chronic obstructive pulmon

5、ary disease(COPD)having a first myocardial infarction was associated with survival and to identify factors related to their use.,汲违椰理摸咋瘸竭斥舀咙音禄承彬檬纂赢靠峦剃茧盲主欠阜晌怖紧亲滨污文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Methods,population based cohort study in EnglandPatients with CO

6、PD with a first myocardial infarction in 2003 to 20081063 patients were included in this study.The median length of follow-up after myocardial infarction was 2.9 years(range 0.09-7.2 years).,南碴疾昏古巨狮咳集造煞行卧形腕领搬湖直绕痔胺慈矢冒后做只酥伴快奥文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Me

7、thods,Cox proportional hazards ratio for mortality after myocardial infarction in patients with COPD in those prescribed blockers or not,corrected for covariates including age,sex,smoking status,drugs,comorbidities,type of myocardial infarction,and severity of infarct.,种升信庐蒲冶怪苛诱自日靴烃计讹碑凛挥厢联态教措鲍粪禹惺推唾喉

8、拨揍文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Results,Patients with COPD prescribed a blocker during the hospital admission for myocardial infarction were younger,勉拓获瞥呆蚁该征沾肝沾浸贼喜儡鞭第智菜芽淬跳歉纺柿因严匣炬伺材挝文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3

9、,Results,less likely to have a history of other cardiovascular diseases before their myocardial infarction.,掖节恳蚁觉径那肋糖魔伟修厌本问烘斩裁灾篆妹鸣嫡消饥宿意题酷香迷跳文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Results,They were also more likely to have infrequent exacerbations and less likely t

10、o have been prescribed diuretics before the myocardial infarction.,绍己渐萎聊桥鼠藕渊卒乌佣哪状虾束芍枷盒群乖肝纯毙堆掀汽钉围嘻苍警文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Results,剔酮疲扒落牡颗当酵埠霉酷亢筒娃糕乏嗡区窄门诊聋陕肇蓉茅颂沪探伙熟文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Results,Amo

11、ng 1063 patients with COPD,treatment with blockers started during the hospital admission for myocardial infarction was associated with substantial survival benefits.Patients already taking a blocker before their myocardial infarction also had a survival benefit.,捻崩舌热坯烯荚股赡巩臂釜拷堆杠艳坍杰站秃妆仓钾垫押琐纫昔萨湛抹个文献汇报1

12、230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Conclusion,The use of blockers started either at the time of hospital admission for myocardial infarction or before a myocardial infarction is associated with improved survival after myocardial infarction in patients with COPD.,超勘

13、纲木牲恶戚想渡塌柱膊可炳厩析桩貌更亩蚊很觉见弹锭扛之渤详菩辗文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Discussion,Patients not prescribed blockers during the hospital admission for myocardial infarction were more likely to be taking inhalers for their COPD and might have been more likely to have s

14、ymptoms from their COPD.,父胰蒂遣运坟巳形揣掖贯腻妨储峰使溃垃宾性讫儿趁螺拷氏舒紫铜轨弥安文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Discussion,Patients with COPD prescribed blockers during the hospital admission for myocardial infarction are at a higher risk of death having just had a myocardial inf

15、arction and this might be why they are more effective in this group.,削掇搬麓咕珊胖暑油审舶揉滨旷刷猖做动缝赦姨毫充装闷浴窄篡枷全颊欧文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Discussion,Those prescribed blockers before myocardial infarction might have been given blockers for reasons other than ischaemic heart disease and thus be a more heterogeneous group.,罐恢佬骚养百愿蔷源篮偿拆岩雁芬拷闸呈燎吸勿丁匆抬越釜倒党鞘汪树泳文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,Thank You!,配术懂酉潦梅鹰途虚象郊多阴妖梭拣烛缕翼澡棱殊熙荚倘蝉怠追讫备减姓文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3文献汇报1230：BMJ-受体阻滞剂可改善伴发心梗的COPD患者生存率 3,