医学双核素心肌断层显像方法课件.ppt
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1、双核素心肌断层显像方法,仪器 采用 elscint varicam 双探头SPECT (GE公司提供),配备超高能准直器 (UHEC)。 双探头采用90度垂直位(L-mode) 进行分步采集。,体位患者取仰卧位,双手抱头充分暴 露心前区。探头尽量贴近患者以最大限度增 加计数,减少噪声。,采集条件采 集 程 序 为 系统 自 带双核素断层采集程序 ( HEI/MIBI ECT Dual Isotope) ; 能峰为140kev 及 511kev、窗宽20%;矩阵6464 ;采集时间为 30-35秒;探头旋转角度为90度(由左前至右后共180度)、每3度一帧分步采集。,处理条件 采用滤波反投影法进
2、行重建,分别得到 水平长轴、短轴及垂直长轴三个断面的 图象;滤波函数采用butterworth,截止频 率为0.45, 权重值为4.5。,血糖调节,静脉注射99Tcm-MIBI20mCi,45分钟后测定患者的血糖浓度,将血糖浓度控制在7.9-8.8mmol/L之间。如果患者血糖浓度低于7.8mmol/L需要口服葡萄糖补充,如果血糖浓度高于8.9mmol/L则需要皮下注射胰岛素降低血糖浓度。在血糖控制后10-15min,静脉注射18F-FDG 6-8mCi,一小时后显像。,Case 1 LJZ,History : 67 year - old male, 2 years history of pr
3、ogressive typical exertional angina and inferior myocardial infarction.Cardiac risk factors included age, known history of CAD. The resting ECG revealed sinus bradycardia and evidence of an old inferior myocardial infarction.,Clinical course,Cardiac catheterization revealed a 100% LAD lesion and 90%
4、 narrowing of the right coronary artery.The patient underwent successful coronary bypass surgery .,DISA imaging protocol,MIBI Plasma glucose FDG DISA 0 40 60 120(min)Plasma glucose 140160mg%.Plasma glucose level 140mg%, 50-75g glucose. Diabetes mellitus, Insulin was subcutaneously injected according
5、 to the plasma glucose.,Case 2 WCD,A 62-year-old female with no past cardiac history presented with a 6 month history of exertional chest pain with both typical and atypical feature. Cardiac risk factors included hypercholesterolemia, family history of CAD.The resting ECG revealed normal.,Hospital c
6、ourse,Cardiac catheterization : LAD 90% , LCX 80%, RCA 60%Clinical diagnosis: CAD Angina pectorisThe patient underwent CABG.,Case 3 LJX,44-year-old male without known CAD presented with a 3 year history of atypical chest pain and dyspnea on exertion. Cardiac risk factors included cigarette smoking.N
7、o history of hypertension , diabetes mellitus .ECG revealed nonsepecific T wave abnormalities.Echocardiography revealed dilated left ventricle and atrium.Severe left ventricular hypokinesis.LVEF=25%,Clinical course,Cardiac catheterization : Three coronary vessels.There was a 80% LAD lesion, 90% narr
8、ow of the left circumflex artery and 50% lesionin the right coronary artery . One month later the patient underwent CABG.,Case 4 GTB,A 58-year-old man presented with mild congestive heart failure 1 year. He had often experienced a chest tightness, and shortness of breath. Cardiac risk factors includ
9、ed age and hypercholesterolemia.The resting ECG revealed LBBB.The resting MIBI - FDG SPECT(DISA) was performed.,Clinical course,Cardiac catheterization: three coronary artery disease , LAD 80% LCX 60% RCA 95%The patient underwent PTCA of mid RCA lesion.,Case 5,A man 52 - year - old presented with pr
10、ogressive exertional angina despitemaximal medical therapy. He had had two previous myocardial infarction.Cardiac risk factors included known CAD, age, hypertension and family history of CAD.His resting ECG revealed evidence of an old anterior myocardial infarction.,Clinical course,Cardiac Catheteri
11、zation:100% LAD lesion ,100% proximal circumflex marginal lesion. Ventriculogram revealed an anteroapical aneurysm.The patient underwent CABG andneurysmectomy.,Case 6 CBK,A 66-year -old without know CAD presented with recent onset of chest fullness on exertion, which was relieved with rest. Cardiac
12、risk factors included diabetes mellitus and tobacco use . The resting ECG was normal.,Clinical course,Cardiac catheterization: 90% stenosis of LAD.The patient underwent successful of PTCA and stent of the proximal LAD lesion.,Case 7 Hsyi,A 67 year - old male presented with atypical chest pain and sh
13、ortness of breath . He had experienced an anterior myocardial infarction 8 year prior. He had stopped smoking cigarettes,and his hyperlipidemia and hypertension were well controlled with medication. The resting ECG revealed an old anteriormyocardial infarction.,1、病毒性肝炎:由病毒造成的肝炎按照其病毒系列不同分为甲、乙、丙、丁、戊和庚
14、共六种类型病毒性肝炎。能引起肝脏细胞肿胀,是世界上流传广泛,危害很大的传染病之一。 1908年,才发现病毒也是肝炎的致病因素之一。1947年,将原来的传染性肝炎(infectious hepatitis)称为甲型肝炎(Hepatitis A, HA);血清性肝炎(serum hepatitis)称为乙型肝炎(Hepatitis B, HB)。1965年人类首次检测到乙型肝炎的表面抗原。 我国经济和科学技术日益发展,学术文化领域百家争鸣,(df高血压958心脏病983u6糖尿病87fr)特别是思想家的革新精神,为中医学理论的创新和突破性进展,提供了有利的文化背景。宋代陈无择著三因极一病证方论一书
15、,(45传染病q566丙肝964jo乙肝28jgsx甲肝gh)提出三因学说;并产生了最具盛名四大学派,刘完素倡导火热论;张从正力倡“攻邪论”;李杲提出“内伤脾胃,百病由生”的理论;朱震亨创造性地阐明了相火的演变规律。编辑本段明清时期(df肺25s血液f369血小板t5172红血球gdf55m白血球fd2)是中医学理论综合汇编、深化发展,临床各科辨证体系丰富、提高阶段。如明代楼英的医学纲目和王肯堂的证治准绳,清代吴谦等编著的医宗金鉴和陈梦雷主编的古今图书集成医部全录等。王清任著医林改错,注重实证研究,(df高血压958心脏病983u6糖尿病87fr)纠正了古医籍中关于解剖知识的某些错误,肯定了“
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