病理学绪论病理学图片Introdu.ppt

Pathology,Second Edition Editor in chief:CHEN Jie and LI GandiPeoples Medical Publishing House,Textbook,Introduction to pathology,Peking Union Medical CollegeChen Jie,Introduction to pathology,A bridging discipline involving both basic science and clinical practice.Devoted to the study of the structural and functional changes in cells,tissues and organs that underlie disease.To explain the whys and wherefores of the signs and symptoms of the patients.Providing a sound foundation for rational clinical care and therapy.,Pathology,The study of etiology of the diseaseThe study of pathogenesis of diseaseThe study of morphological changes of diseaseThe most important diagnosis in modern medical practiceThe important step in evidence-based medicineThe functional consequences of the morphologic changes(clinical significance),Pathology,Biopsy Histopathology Cytology Electromicroscopy Resected specimens HistochemistryAutopsy MicrobiologyCell&tissue cultureimmunohistochemistryMolecular pathology,Etiology,Intrinsic or geneticAcquired infectious nutritional chemical physical,Pathogenesis,Initial stimulus-ultimate expression of diseaseDefective gene-cysts and fibrosis,Morphologic changes,Structural alterations cells tissues organsCharacteristic of the diseaseDiagnostic of the etiologic process,Clinical significance,Functional abnormalityClinical features(symptoms and signs)Clinical coursePrognosis of the disease,“As is our pathology,so is our medicine”“病理为医之本”,Sir William Osler 1849-1919,基础医学课目中与临床最接近的当推病理学，因为它是临床与基础之间的桥梁，要学好临床先要学好病理学，我毕业后才认识这个道理。原想加学一年病理学以资祢补，可是没能做到，至今引为遗憾。著名医学家张孝骞,谢 谢,